Northwestern University Feinberg School of Medicine

Center for Genetic Medicine

Geoffrey S Kansas, PhD

Geoffrey S Kansas, PhD

Associate Professor of Microbiology-Immunology

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Focus of Work

Bio

My laboratory is interested in signaling mechanisms which control T helper cell differentiation and traffic. We are currently focused on two areas: functions of p38 MAP kinases (MAPK) and the role of a transcription factor KLF2 in these processes. Towards this end, we have produced novel mouse models which will allow us to test the role of the different isoforms of p38 (of which there are 4) in T helper differentiation and expression of key leukocyte adhesion molecules; and to determine the r...[Read full text]My laboratory is interested in signaling mechanisms which control T helper cell differentiation and traffic. We are currently focused on two areas: functions of p38 MAP kinases (MAPK) and the role of a transcription factor KLF2 in these processes. Towards this end, we have produced novel mouse models which will allow us to test the role of the different isoforms of p38 (of which there are 4) in T helper differentiation and expression of key leukocyte adhesion molecules; and to determine the role of KLF2 downregulation in T helper biology generally.[Shorten text]

Keywords

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Gene RegulationInflammationMolecular GeneticsImmunologyStem Cells

Education and Certification

  • PhD: Stanford University, Cancer Biology (1984)
  • Postdoctoral Fellowship: Stanford University (1985)
  • Postdoctoral Fellowship: University of Iowa (1990)

Contact

312-908-3237

Ward Building Room 6-313
303 E Chicago Avenue
Chicago IL 60611

Links

Institutes and Centers