Events: Center for Genetic Medicine: Feinberg School of Medicine: Northwestern University

Mar

28

Danielle Maatouk Memorial Lectureship featuring Dr. Peter Koopman, Professor of Developmental Biology at The University of Queensland

Chicago - 4:00 PM - 5:30 PM

Please join us for a Center for Reproductive Science Lectureship honoring Dr. Danielle Maatouk.

We welcome Peter Koopman, PhD, DSc, FAA, Professor of Developmental Biology, NHMRC Senior Principal Research Fellow, Institute for Molecular Bioscience, The University of Queensland, Brisbane Australia.

Danielle Marie Maatouk, received her Ph.D. from the University of Florida in Molecular Genetics. She then worked as a Postdoctoral Fellow in the Department of Biology and Genetics at Duke University, before working at Northwestern University as an Assistant Professor of Obstetrics and Gynecology.Danielle Maatouk

Danielle passed away on November 13th, 2016, at the age of 39, after a two-and-a-half-year battle with aggressive colon cancer. She is survived by her husband, Christopher Futtner, and their two young children. She was an exceptional scientist who studied how changes in the epigenome regulate gene expression and cell fate determination during fetal development.

In her own words:

The goal of my lab is to investigate how changes in the epigenome regulate gene expression and cell fate determination during fetal development. Specifically, I will investigate chromatin remodeling during sex determination and uncover regulatory elements that modulate the activity of genes required for ovary and testis formation. I will use this information to aid in the diagnosis of patients with Disorders of Sexual Development, the majority of whom never receive a genetic diagnosis.

An innovator, a teacher, a colleague, a friend. Science will miss Danielle Maatouk but her legacy lives on in all of us in the department, her students, and in the next generation of learners who will reveal the fundamentals of sex.

Donations continue to be accepted for this Memorial Lectureship. To make a donation, please contact the CRS Executive Director at crs@northwestern.edu

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Apr

02

Genotypes to phenotypes: Lessons from the human genome and transcriptome - Barbara Stranger, PhD

Chicago - 2:00 PM - 3:00 PM

Barbara E. Stranger, PhD
Assistant Professor, Department of Medicine, Section of Genetic Medicine
Core Member, Institute for Genomics and Systems Biology
Fellow, Center for Translational Data Science
The University of Chicago

This talk will illustrate how knowledge of the human transcriptome can inform on genome function and complex trait variation. The lecture will include examples of the genetic basis of gene regulation, applications to immune-mediated phenotypes, and the effects of sex on transcriptional variation.

Dr. Barbara Stranger is an Assistant Professor in the Department of Genetic Medicine at the University of Chicago. In addition, she is a Faculty Fellow in the Institute for Genomics and Systems Biology and The Center for Translational Data Science. Her lab analyzes multi-dimensional human genomics data, particularly transcriptome data and genetic variation data, in the context of health and disease. She develops effective analytic approaches for large-scale analysis of functional genomics data, and applies systems biology methodologies to integrate data of different types to inform biology of complex traits. She is a member of the Analysis Working Group (AWG) of NIH s Genotype-Tissue Expression (GTEx) project, and leads the Sex Differences Working Group within the GTEx AWG. Current projects in her laboratory focus on understanding mechanisms and consequences of sexual dimorphism in: 1) Genetic regulation of gene expression in GTEx, 2) Genetic regulation of protein expression in GTEx, 3) Genetic architecture of neuropsychiatric traits, and 4) Genetics and genomics of cancer and response to therapy. She has a longstanding interest in evolution, and also applies the tools and approaches of population and evolutionary genetics to her research areas.

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Apr

05

Simpson Querrey Center for Epigenetics Forum on Biochemistry, Epigenetics, and Metabolism (BEaM)

Chicago - 3:30 PM - 5:00 PM

The BEAM Forum is a data group where Simpson Querrey Epigenetics Center members present ongoing work being conducted in the Center. It is a great opportunity to get feedback on your work from colleagues, and to make new connections and foster new collaborations within the Center.

The forum is normally held every other Friday from 3:30-5:00 pm throughout the year in Baldwin Auditorium. Two presenters will give 30 minute talks each week with 10 minutes for discussion and questions. We invite all labs associated with the SQE Center to participate. We welcome presentation from students, techs, postdocs, and PIs. Presenting work-in-progress is always encouraged!

Pizza and soda is provided.

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Apr

19

Simpson Querrey Center for Epigenetics Forum on Biochemistry, Epigenetics, and Metabolism (BEaM)

Chicago - 3:30 PM - 5:00 PM

The BEAM Forum is a data group where Simpson Querrey Epigenetics Center members present ongoing work being conducted in the Center. It is a great opportunity to get feedback on your work from colleagues, and to make new connections and foster new collaborations within the Center.

The forum is normally held every other Friday from 3:30-5:00 pm throughout the year in Baldwin Auditorium. Two presenters will give 30 minute talks each week with 10 minutes for discussion and questions. We invite all labs associated with the SQE Center to participate. We welcome presentation from students, techs, postdocs, and PIs. Presenting work-in-progress is always encouraged!

Pizza and soda is provided.

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Apr

25

MBS Department Seminar: Aseem Ansari, UW-Madison. Title: "Turning on the switch: Drugging the Genome"

Evanston - 12:30 PM - 1:30 PM

MBS Department Seminar

Aseem Ansari, UW-Madison

Title: Turning on the switch: Drugging the Genome

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May

03

Simpson Querrey Center for Epigenetics Forum on Biochemistry, Epigenetics, and Metabolism (BEaM)

Chicago - 3:30 PM - 5:00 PM

The BEAM Forum is a data group where Simpson Querrey Epigenetics Center members present ongoing work being conducted in the Center. It is a great opportunity to get feedback on your work from colleagues, and to make new connections and foster new collaborations within the Center.

The forum is normally held every other Friday from 3:30-5:00 pm throughout the year in Baldwin Auditorium. Two presenters will give 30 minute talks each week with 10 minutes for discussion and questions. We invite all labs associated with the SQE Center to participate. We welcome presentation from students, techs, postdocs, and PIs. Presenting work-in-progress is always encouraged!

Pizza and soda is provided.

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May

03

CLP Seminar: David Baker, PhD

No Location - 4:00 PM - 5:00 PM

CLP Seminar: David Baker, PhD

David Baker is Professor of Biochemistry, Director of the Institute for Protein Design, Investigator of the Howard Hughes Medical Institute, and adjunct professor of Genome Sciences, Bioengineering, Chemical Engineering, Computer Science, and Physics at the University of Washington. He received his Ph.D. degree in biochemistry with Randy Schekman at the University of California, Berkeley and did postdoctoral work in biophysics with David Agard at UCSF. His research group is focused on the prediction and design of macromolecular structures, interactions and functions. Dr. Baker received young investigator awards from the National Science Foundation and the Beckman Foundation, and the Packard Foundation fellowship in Science and Engineering. He has also received the Irving Sigal Young Investigator award from the Protein Society and the Overton Prize from the International Society of Computational Biology. He is a recipient of the Feynman Prize from the Foresight Institute, the AAAS Newcomb_Cleveland prize, the Sackler prize in biophysics, and the Centenary award from the Biochemical society. He is a member of the National Academy of Sciences and the American Academy of Sciences. His research group is a world leader in computational protein design and protein structure prediction.

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May

09

DNA Technologies to Improve Diagnosis and Treatment of Autism Spectrum Disorders - Jonathan Sebat, PhD

Chicago - 2:00 PM - 3:00 PM

The Center for Autism and Neurodevelopment of Northwestern University Feinberg School of Medicine welcomes you to attend a lecture featuring:

Jonathan Sebat, PhD
Director, Beyster Center for Genomics of Psychiatric Disease
Professor of Psychiatry, Cellular and Molecular Medicine, and Pediatrics
Institute for Genomic Medicine
University of California, San Diego

Dr Jonathan Sebat is a leader in the field of psychiatric genetics, and an expert in the genomic characterization of autism by Whole Genome Sequencing (WGS). His research has made substantial contributions to our current knowledge of genome-wide patterns of germline mutation and the contribution of rare and de novo genetic variants to risk for common disease. His early research on patterns of structural genetic variation (SV) in the human genome led the initial discovery of the widespread abundance of SV in the human genome. Application of SV detection methods to neuropsychiatric disorders, including autism spectrum disorders and schizophrenia has served to elucidate the role of rare structural variants in neuropsychiatric disorders. Dr. Sebat is the Director of the Beyster Center for Psychiatric Genomics, where he leads an interdisciplinary team in the clinical and genomic analysis of patient cohorts at UCSD and Rady Children s Hospital. In addition, he has led multiple large consortium efforts including as chair of the CNV analysis group for the Psychiatric Genomics Consortium and a co-lead investigator on the Human Genome Structural Variation Consortium (HGSVC) where his group has led interdisciplinary teams on the analysis of genomic and clinical datasets on large cohorts.

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May

17

Simpson Querrey Center for Epigenetics Forum on Biochemistry, Epigenetics, and Metabolism (BEaM)

Chicago - 3:30 PM - 5:00 PM

The BEAM Forum is a data group where Simpson Querrey Epigenetics Center members present ongoing work being conducted in the Center. It is a great opportunity to get feedback on your work from colleagues, and to make new connections and foster new collaborations within the Center.

The forum is normally held every other Friday from 3:30-5:00 pm throughout the year in Baldwin Auditorium. Two presenters will give 30 minute talks each week with 10 minutes for discussion and questions. We invite all labs associated with the SQE Center to participate. We welcome presentation from students, techs, postdocs, and PIs. Presenting work-in-progress is always encouraged!

Pizza and soda is provided.

more

Jun

11