News and Announcements
Read the latest news from Northwestern University Feinberg School of Medicine’s Center for Genetic Medicine. The links below take you to articles where you can learn more about our members' latest achievements, awards and honors.
01.14.2022The laboratory of YouYang Zhao, PhD, developed a unique nanoparticle to deliver genome editing technology, including CRISPR/Cas9, to vascular endothelial cells.
01.06.2022A new Northwestern Medicine study reports that DNA manifested as knot-like folds and third rungs between DNA’s two strands may drive cancer development and an important regulatory enzyme could be associated with the formation of these unusual structures.
12.20.2021The protein UBR7 acts as a histone chaperone and regulates nucleotide metabolism, making UBR7 among the first proteins known to affect both processes.
12.17.2021Northwestern Medicine scientists have discovered a biomarker for one type of autism within cerebrospinal fluid, according to a recent study.
12.16.2021Mutations in a histone regulator protein are connected to both a rare neurodevelopmental disorder and to some cancers, according to a recent study.
12.10.2021Northwestern investigators have discovered the molecular signature of a subset of dopaminergic neurons that increases their vulnerability to degeneration.
12.07.2021Long chains of fatty acids in the lysosome are associated with a degenerative form of Gaucher disease, an inherited condition related to Parkinson’s disease.
11.23.2021A combination of drugs could fix the broken lysosomal enzyme pathway in Parkinson’s disease-afflicted neurons, according to a recent study.
11.10.2021Fatty acid uptake produces an epigenetic modification that is required for cancer metastasis, according to a study published in Nature.
11.08.2021The damaging effects of toxic proteins created in one inherited form of amyotrophic lateral sclerosis (ALS) are mediated by an enzyme called SPOP.
10.28.2021Human cells use a protein named TBC1D5 to “trap and kill” influenza A viruses inside host cells, but the virus encodes its own protein to disable this defense.
10.21.2021TG2, an enzyme known to help cancers spread more quickly, also plays a role in regulating T-cells — opening the door to dual inhibition, according to a recent Northwestern Medicine study.
10.08.2021Northwestern is part of the Impact of Genomic Variation on Function (IGVF) Consortium, a $185 million National Institutes of Health (NIH) project that will explore the millions of genetic variants that cause disease around the world.
10.07.2021An especially deadly subtype of T-cell lymphoma is distinguished by unique mutations in the JAK-STAT pathway, according to a recent Northwestern Medicine study.
10.04.2021A unique interaction between an excitatory neural receptor and a chloride transporter are critical for development of adult-born neurons in the dentate gyrus.
10.01.2021Northwestern’s Brain Tumor SPORE — part of the Lurie Cancer Center — is now three years old, and the bench to bedside process is producing results.
09.24.2021Harmful side effects from a common chemotherapy drug could be prevented in patients with a specific mutation by targeting retinoic acid receptors, according to a recent study.
09.23.2021Northwestern Medicine scientists have characterized several variants of the gene GRIK2 that cause nonsyndromic neurodevelopmental disorder.
09.15.2021Epigenetic aging could serve as a promising biomarker for measuring long-term cardiovascular health and disease risk, according to a recent Northwestern Medicine study.
- 09.03.2021
Northwestern Medicine scientists have identified a critical checkpoint in transcription elongation, the process of synthesizing RNA from a DNA template.
08.31.2021Genomic autopsy of young individuals who experienced sudden death revealed many had known genetic variants that are associated with cardiomyopathy.
08.04.2021Losing a check on T-cell activation in cutaneous T-cell lymphoma cells is associated with poor outcomes, according to a study published in Blood.
08.03.2021Using circulating tumor DNA to identify patients at risk for urothelial cancer relapse after surgical resection could help improve post-surgery treatment, according to a new study.
06.09.2021Northwestern Medicine scientists have described a method of reconstructing the three-dimensional structure of chromosomes in cancer cells and matching those chromosomes with counterpart oncogenes.
05.21.2021Northwestern Medicine scientists have developed Nuc-MS, a new method to capture the protein composition of whole nucleosomes without losing information.
05.05.2021Two Northwestern Medicine studies are improving the understanding of epigenetic mechanisms in cancer development and progression, and identifying novel cancer driver genes that may help identify patients who will benefit from immunotherapy.
04.30.2021Mitochondria play a key role in forming the lymphatic vasculature by acting as a metabolic sensor during the migration of lymphatic progenitor cells from the veins.
04.20.2021Northwestern Medicine scientists have discovered a mechanism that makes a prostate cancer-causing protein called FOXA1 more resilient, according to a recent study.
- 04.15.2021
Northwestern Medicine investigators are advancing the understanding of two groups of transcription factors and their role in many neurodevelopmental diseases and cancers, which is essential for developing novel therapeutic approaches.