News and Announcements
Read the latest news from Northwestern University Feinberg School of Medicine’s Center for Genetic Medicine. The links below take you to articles where you can learn more about our members' latest achievements, awards and honors.
10.21.2021TG2, an enzyme known to help cancers spread more quickly, also plays a role in regulating T-cells — opening the door to dual inhibition, according to a recent Northwestern Medicine study.
10.08.2021Northwestern is part of the Impact of Genomic Variation on Function (IGVF) Consortium, a $185 million National Institutes of Health (NIH) project that will explore the millions of genetic variants that cause disease around the world.
10.07.2021An especially deadly subtype of T-cell lymphoma is distinguished by unique mutations in the JAK-STAT pathway, according to a recent Northwestern Medicine study.
10.04.2021A unique interaction between an excitatory neural receptor and a chloride transporter are critical for development of adult-born neurons in the dentate gyrus.
10.01.2021Northwestern’s Brain Tumor SPORE — part of the Lurie Cancer Center — is now three years old, and the bench to bedside process is producing results.
09.24.2021Harmful side effects from a common chemotherapy drug could be prevented in patients with a specific mutation by targeting retinoic acid receptors, according to a recent study.
09.23.2021Northwestern Medicine scientists have characterized several variants of the gene GRIK2 that cause nonsyndromic neurodevelopmental disorder.
09.15.2021Epigenetic aging could serve as a promising biomarker for measuring long-term cardiovascular health and disease risk, according to a recent Northwestern Medicine study.
09.03.2021Northwestern Medicine scientists have identified a critical checkpoint in transcription elongation, the process of synthesizing RNA from a DNA template.
08.31.2021Genomic autopsy of young individuals who experienced sudden death revealed many had known genetic variants that are associated with cardiomyopathy.
08.04.2021Losing a check on T-cell activation in cutaneous T-cell lymphoma cells is associated with poor outcomes, according to a study published in Blood.
08.03.2021Using circulating tumor DNA to identify patients at risk for urothelial cancer relapse after surgical resection could help improve post-surgery treatment, according to a new study.
06.09.2021Northwestern Medicine scientists have described a method of reconstructing the three-dimensional structure of chromosomes in cancer cells and matching those chromosomes with counterpart oncogenes.
05.21.2021Northwestern Medicine scientists have developed Nuc-MS, a new method to capture the protein composition of whole nucleosomes without losing information.
05.05.2021Two Northwestern Medicine studies are improving the understanding of epigenetic mechanisms in cancer development and progression, and identifying novel cancer driver genes that may help identify patients who will benefit from immunotherapy.
04.30.2021Mitochondria play a key role in forming the lymphatic vasculature by acting as a metabolic sensor during the migration of lymphatic progenitor cells from the veins.
04.20.2021Northwestern Medicine scientists have discovered a mechanism that makes a prostate cancer-causing protein called FOXA1 more resilient, according to a recent study.
- 04.15.2021
Northwestern Medicine investigators are advancing the understanding of two groups of transcription factors and their role in many neurodevelopmental diseases and cancers, which is essential for developing novel therapeutic approaches.
04.13.2021A massive trove of information produced in a Northwestern-led study will lay the groundwork for understanding sex-related differences in health and disease for decades to come.
03.24.2021Northwestern’s investment in next-generation sequencing is leading to unprecedented avenues of discovery.
03.04.2021Northwestern Medicine scientists discovered mutations in a scaffolding protein contributes to dystonia, an incurable movement disorder.
- 03.01.2021
A team of Northwestern Medicine investigators have identified specific genetic regions that regulate the expression of genes associated with inherited cardiomyopathy and disease severity.
02.25.2021Blocking the arginine methylation pathway, which helps brain tumor cells proliferate by promoting cell division, could improve cancer therapies, according to a recent study.
02.15.2021T-cell acute lymphoblastic leukemia hijacks a signaling pathway to produce nucleotides, a basic building block of life that fuels the growth and spread of the cancer, according to a recent study.
02.12.2021Northwestern Medicine scientists have detailed the diverse function of CDK9-containing complexes and their impact on gene expression in a recent study published in the journal Genes and Development.
01.19.2021A new study published in Nature Communications has found evidence deep within the skin about the mechanisms controlling skin repair and renewal.
01.04.2021Calcium channels commonly found in immune cells are also present in the brain and regulate synaptic plasticity, according to a recently published study.
12.28.2020Listen to the year's most popular episodes of the Breakthroughs podcast, featuring Northwestern Medicine experts discussing COVID-19 research.
- 12.18.2020
Northwestern Medicine scientists have developed a new high-throughput sequencing tool to test how drugs interact with genetically modified cells.