News and Announcements
Read the latest news from Northwestern University Feinberg School of Medicine’s Center for Genetic Medicine. The links below take you to articles where you can learn more about our members' latest achievements, awards and honors.
A protein gives motile cilia part of their structure, according to a recent Northwestern Medicine study.
A novel compound using diphtheria toxin to attack a signaling pathway implicated in as many as 50 percent of cancers slowed tumor growth, according to a recent study.
The gene transcription machinery that controls circadian rhythms also regulates insulin release in the pancreas, according to a Northwestern Medicine study.
A genetic screen has revealed previously unknown regulators of Foxp3, a transcription factor that, when deactivated, may improve patient response to aggressive cancers.
Genetic mutations in desmoplakin cause left ventricular cardiomyopathy, rather than right ventricular cardiomyopathy as previously believed, according to a recent study.
A novel method to map protein-protein interactions between viruses and their hosts more precisely than current methodologies may help improve the design of antiviral drugs and therapeutic strategies.
Northwestern Medicine scientists have discovered an alternate mechanism for aberrant gene splicing that contributes to T-cell lymphoblastic leukemia, according to a recent study.
A Northwestern Medicine study has uncovered the molecular mechanisms behind the development of autosomal dominant polycystic kidney disease (ADPKD) and a potential drug target.
A new $15 million gift from University trustees and supporters Louis A. Simpson and Kimberly K. Querrey will establish the Simpson Querrey Institute for Epigenetics at Northwestern University Feinberg School of Medicine, boosting the school’s current efforts to study the effects of environment on the regulation of gene expression.
Mutations in the genes RAS and RAF allow cancer cells to create their own nucleotides, fueling cancer growth, according to a recent study published in Molecular Cell.
Supplementing lab animal diets with a chemical precursor of the molecule NAD+ countered certain age-related declines in circadian rhythm function, according to a recent study.
A new Northwestern Medicine study found important differences in rare skin lymphomas stemming from their specific cell of origin and clinical presentations, according to findings published in Nature Communications.
A new Northwestern Medicine study discovered a new and unexpected function for the transcriptional regulator MLL2/COMPASS.
For the first time, advanced prostate cancer has been treated based on the genomic makeup of the cancer, delaying disease progression for patients with a treatment-resistant form of prostate cancer.
A new study has found that genetic alterations in a rare form of leukemia physically change the architecture of DNA, fueling the replication and spread of cancer cells.
A new Northwestern Medicine study has shed light on the complex phenomenon of liver zonation, showing that a protein known as Wnt is required for correct placement of tight junction and cell adhesion proteins within the liver.
Northwestern Medicine investigators have uncovered a novel pathogenic mechanism used by the bacterium Pseudomonas aeruginosa to promote more severe infections.
A new study has found cells with high numbers of centrioles more quickly migrated through layers of tissue, a process known as radial intercalation, which may provide new insights into the development of many cancers.
A new study has helped solve the mystery of how dysfunctional chromosome folding leads to cancer.
The elevated expression of a gene called LY6K was correlated with increased cancer cell growth and resistance to radiation therapy in glioblastoma, according to a recent Northwestern Medicine study.
A DNA transcription mechanism does not work as previously thought, according to a new Northwestern Medicine study.
A novel genetic toolkit developed by Northwestern Medicine scientists may support the development of customized therapeutic interventions for a breadth of diseases, according to a recent study published in Nature Communications.
A team of Northwestern Medicine investigators identified a specific gene as a key regulator of immune cells called invariant natural killer T cells, which may present therapeutic potential for the treatment of autoimmune diseases.
The development of oligodendrocytes are heavily influenced by an RNA epigenetic regulation mechanism, according to a new study.
Using mathematical modeling and optical imaging they developed themselves, a Northwestern University research team has discovered how chromatin folds at the single-cell level.
People who carry genetic mutations associated with an increased risk for Parkinson’s disease may exhibit minor symptoms long before the disease progresses to affect daily life, according to a study of over 300 patients.
These images illustrate the physical reality Northwestern scientists work within, striving to uncover the mysteries of biology, chemistry and medicine.
Levels of African ancestry in a person’s genome determines the level at which certain genes are expressed, findings that could offer insight into the different risk of diseases.
Scientists have discovered why a specific genetic mutation causes intellectual disability and autism spectrum disorder in children.
A new machine-learning tool demonstrates the clinical potential of ‘junk DNA’ methylation in hepatitis C-associated liver cancer patients without the need for expensive testing.