News and Announcements

A novel compound using diphtheria toxin to attack a signaling pathway implicated in as many as 50 percent of cancers slowed tumor growth, according to a recent study.

A genetic screen has revealed previously unknown regulators of Foxp3, a transcription factor that, when deactivated, may improve patient response to aggressive cancers.

A novel method to map protein-protein interactions between viruses and their hosts more precisely than current methodologies may help improve the design of antiviral drugs and therapeutic strategies.

A Northwestern Medicine study has uncovered the molecular mechanisms behind the development of autosomal dominant polycystic kidney disease (ADPKD) and a potential drug target.

Mutations in the genes RAS and RAF allow cancer cells to create their own nucleotides, fueling cancer growth, according to a recent study published in Molecular Cell.

A new Northwestern Medicine study found important differences in rare skin lymphomas stemming from their specific cell of origin and clinical presentations, according to findings published in Nature Communications.

For the first time, advanced prostate cancer has been treated based on the genomic makeup of the cancer, delaying disease progression for patients with a treatment-resistant form of prostate cancer.

A new Northwestern Medicine study has shed light on the complex phenomenon of liver zonation, showing that a protein known as Wnt is required for correct placement of tight junction and cell adhesion proteins within the liver.

A new study has found cells with high numbers of centrioles more quickly migrated through layers of tissue, a process known as radial intercalation, which may provide new insights into the development of many cancers.

The elevated expression of a gene called LY6K was correlated with increased cancer cell growth and resistance to radiation therapy in glioblastoma, according to a recent Northwestern Medicine study.

A novel genetic toolkit developed by Northwestern Medicine scientists may support the development of customized therapeutic interventions for a breadth of diseases, according to a recent study published in Nature Communications.

The development of oligodendrocytes are heavily influenced by an RNA epigenetic regulation mechanism, according to a new study.

People who carry genetic mutations associated with an increased risk for Parkinson’s disease may exhibit minor symptoms long before the disease progresses to affect daily life, according to a study of over 300 patients.

Levels of African ancestry in a person’s genome determines the level at which certain genes are expressed, findings that could offer insight into the different risk of diseases.

A new machine-learning tool demonstrates the clinical potential of ‘junk DNA’ methylation in hepatitis C-associated liver cancer patients without the need for expensive testing.