News and Announcements
Read the latest news from Northwestern University Feinberg School of Medicine’s Center for Genetic Medicine. The links below take you to articles where you can learn more about our members' latest achievements, awards and honors.
Northwestern Medicine investigators have discovered a potential therapeutic target for the most common type of pancreatic cancer, according to a study published in Developmental Cell.
A transcription factor associated with androgen receptor activity in prostate cancer has a newly discovered role in controlling lipid biosynthesis.
Northwestern Medicine scientists identified critical regulatory processes that govern differentiation in embryonic stem cells.
Isabella Salamone, an eighth-year student in the Driskill Graduate Program in Life Sciences, was lead author of a study published in the Journal of Clinical Investigation, which found that glucocorticoid steroids improved muscle performance through distinct, sex-specific molecular pathways.
Epigenetic markers of cognitive aging can predict outcomes on cognitive tests later in life, according to a recent Northwestern Medicine study.
A recent study published in Nature Genetics identified 10 new genetic regions associated with Brugada syndrome, a cardiac arrhythmia disorder.
Daniel Brat, MD, PhD, has been heavily involved in the process of moving molecular genetic biomarkers for glioma from the bench to the beside.
Glucocorticoid steroids improved muscle performance through distinct, sex-specific mechanisms, according to a Northwestern Medicine study.
Northwestern Medicine scientists discovered functional links between dozens of potassium channel gene variants and neonatal epilepsy.
A genetic analysis indicates eosinophilic colitis is distinct from other eosinophilic gastrointestinal diseases and inflammatory bowel disease, according to a recent study.
Idiopathic dilated cardiomyopathy (DCM) was found to have a familial etiology in 30 percent of individuals diagnosed with DCM, and the overall risk for a family member of developing DCM was nearly 20 percent by the age of 80.
Sequencing known cardiac arrythmia genes in more than 20,000 people without an indication for genetic testing identified pathogenic variants in nearly one percent of individuals.
A genetic mutation changing just one base pair of nucleotides greatly increases risk of a lethal subtype of childhood acute lymphoblastic leukemia, according to a recent study.
The laboratory of YouYang Zhao, PhD, developed a unique nanoparticle to deliver genome editing technology, including CRISPR/Cas9, to vascular endothelial cells.
A new Northwestern Medicine study reports that DNA manifested as knot-like folds and third rungs between DNA’s two strands may drive cancer development and an important regulatory enzyme could be associated with the formation of these unusual structures.
The protein UBR7 acts as a histone chaperone and regulates nucleotide metabolism, making UBR7 among the first proteins known to affect both processes.
Northwestern Medicine scientists have discovered a biomarker for one type of autism within cerebrospinal fluid, according to a recent study.
Mutations in a histone regulator protein are connected to both a rare neurodevelopmental disorder and to some cancers, according to a recent study.
Northwestern investigators have discovered the molecular signature of a subset of dopaminergic neurons that increases their vulnerability to degeneration.
Long chains of fatty acids in the lysosome are associated with a degenerative form of Gaucher disease, an inherited condition related to Parkinson’s disease.
A combination of drugs could fix the broken lysosomal enzyme pathway in Parkinson’s disease-afflicted neurons, according to a recent study.
Fatty acid uptake produces an epigenetic modification that is required for cancer metastasis, according to a study published in Nature.
The damaging effects of toxic proteins created in one inherited form of amyotrophic lateral sclerosis (ALS) are mediated by an enzyme called SPOP.
Human cells use a protein named TBC1D5 to “trap and kill” influenza A viruses inside host cells, but the virus encodes its own protein to disable this defense.
TG2, an enzyme known to help cancers spread more quickly, also plays a role in regulating T-cells — opening the door to dual inhibition, according to a recent Northwestern Medicine study.
Northwestern is part of the Impact of Genomic Variation on Function (IGVF) Consortium, a $185 million National Institutes of Health (NIH) project that will explore the millions of genetic variants that cause disease around the world.
An especially deadly subtype of T-cell lymphoma is distinguished by unique mutations in the JAK-STAT pathway, according to a recent Northwestern Medicine study.
A unique interaction between an excitatory neural receptor and a chloride transporter are critical for development of adult-born neurons in the dentate gyrus.
Northwestern’s Brain Tumor SPORE — part of the Lurie Cancer Center — is now three years old, and the bench to bedside process is producing results.