News and Announcements

A new immunotherapy treatment for recurrent B-cell lymphoma was found to be safe in a trial of nearly 350 patients, according to a study published in The Lancet.

Biological sex has a small but ubiquitous influence on gene expression in almost every type of human tissue, according to a new study.

Genomic alterations in prostate cancer therapeutic targets were found to be similar between African American and European American men, suggesting that existing precision medicine approaches could equally benefit both groups if applied equitably, according to a recent study.

A Northwestern Medicine scientist and collaborators have used an AI-enhanced precision medicine approach to combine multiple views of human brain development as they seek to provide a roadmap for what causes subtypes of autism spectrum disorder.

A specific cell signaling protein may be used to enhance the sensitivity of medulloblastoma tumors to immunotherapy, potentially improving quality of life for patients with the malignant pediatric brain cancer.

A novel compound using diphtheria toxin to attack a signaling pathway implicated in as many as 50 percent of cancers slowed tumor growth, according to a recent study.

A genetic screen has revealed previously unknown regulators of Foxp3, a transcription factor that, when deactivated, may improve patient response to aggressive cancers.

A novel method to map protein-protein interactions between viruses and their hosts more precisely than current methodologies may help improve the design of antiviral drugs and therapeutic strategies.

A Northwestern Medicine study has uncovered the molecular mechanisms behind the development of autosomal dominant polycystic kidney disease (ADPKD) and a potential drug target.

Mutations in the genes RAS and RAF allow cancer cells to create their own nucleotides, fueling cancer growth, according to a recent study published in Molecular Cell.

A new Northwestern Medicine study found important differences in rare skin lymphomas stemming from their specific cell of origin and clinical presentations, according to findings published in Nature Communications.

For the first time, advanced prostate cancer has been treated based on the genomic makeup of the cancer, delaying disease progression for patients with a treatment-resistant form of prostate cancer.

A new Northwestern Medicine study has shed light on the complex phenomenon of liver zonation, showing that a protein known as Wnt is required for correct placement of tight junction and cell adhesion proteins within the liver.

A new study has found cells with high numbers of centrioles more quickly migrated through layers of tissue, a process known as radial intercalation, which may provide new insights into the development of many cancers.

The elevated expression of a gene called LY6K was correlated with increased cancer cell growth and resistance to radiation therapy in glioblastoma, according to a recent Northwestern Medicine study.