Eva Redei, PhD
David Lawrence Stein Research Professor of Psychiatric Diseases Affecting Children and Adolescents
Professor in Psychiatry and Behavioral Sciences and Physiology
Feinberg School of Medicine
Eva Redei’s major interests include the molecular basis of affective illnesses and stress hyperreactivity. To this end, her laboratory has been using animal models and genetic methods. One of their projects uses quantitative trait loci analysis of multiple behavioral and hormonal traits in a genetic animal model of depression. They have identified multiple loci for each traits and are currently analyzing polymorphisms in candidate genes. Dr. Redei is also a co-investigator on the Mutagenesis Center grant (Joe Takahashi, P.I.), where the project characterizes potential mutants showing enhanced or diminished hormonal and behavioral stress-reactivity.
Redei, E. E. (2008). Molecular genetics of the stress-responsive adrenocortical axis. Ann Med 40, 139-48.
Solberg, L. C., Baum, A. E., Ahmadiyeh, N., Shimomura, K., Li, R., Turek, F. W., Takahashi, J. S., Churchill, G. A. and Redei, E. E. (2006). Genetic analysis of the stress-responsive adrenocortical axis. Physiol Genomics 27, 362-9.
Ahmadiyeh, N., Churchill, G. A., Solberg, L. C., Baum, A. E., Shimomura, K., Takahashi, J. S. and Redei, E. E. (2005). Lineage is an epigenetic modifier of QTL influencing behavioral coping with stress. Behav Genet 35, 189-98.
Baum, A. E., Solberg, L. C., Kopp, P., Ahmadiyeh, N., Churchill, G., Takahashi, J. S., Jameson, J. L. and Redei, E. E. (2005). Quantitative trait loci associated with elevated thyroid-stimulating hormone in the Wistar-Kyoto rat. Endocrinology 146, 870-8.
Solberg, L. C., Baum, A. E., Ahmadiyeh, N., Shimomura, K., Li, R., Turek, F. W., Churchill, G. A., Takahashi, J. S. and Redei, E. E. (2004). Sex- and lineage-specific inheritance of depression-like behavior in the rat. Mamm Genome 15, 648-62.